Are Polynucleotides Better Than Fillers?

Looking to refresh your skin but prefer a natural alternative to traditional dermal fillers? Polynucleotide injections are one of the most exciting innovations in aesthetics right now—and they might just be the solution you’ve been searching for.

From the famous “salmon sperm facial” to advanced injectable treatments, polynucleotides are becoming a go-to for people who want healthier, more radiant skin without invasive procedures. But how do they compare to fillers, and could they be the right choice for you? Let’s take a closer look.

What Are Polynucleotides?

Polynucleotides are natural molecules that form the building blocks of DNA. When injected into the skin, they help repair and regenerate tissue at a cellular level. By stimulating fibroblast activity—which is essential for collagen production and tissue repair—they improve skin elasticity, hydration, and overall smoothness.

The “salmon sperm facial” is one of the most talked-about polynucleotide treatments. Purified DNA from salmon sperm is carefully injected into the skin, encouraging collagen production and enhancing texture and hydration. The result? A radiant, youthful glow without surgery, harsh chemicals, or dramatic changes to your facial features.

Polynucleotides vs. Fillers

Dermal fillers add volume, smooth lines, and sculpt facial features, giving instant, noticeable results. Perfect if you want immediate plumpness or contouring.

Polynucleotides, on the other hand, are regenerative rather than volumising. They work gradually, improving the quality of your skin from within. Over time, your skin becomes firmer, smoother, and better hydrated—making this treatment ideal for those seeking a natural, subtle refresh without altering their facial structure.

Which One Is Right for You?

It comes down to your goals:

• Dermal fillers: Instant volume, contour, and wrinkle smoothing. Ideal for noticeable, immediate changes. Requires regular maintenance.

• Polynucleotides: Gradual skin rejuvenation, improved texture, hydration, and elasticity. Perfect if you want subtle, natural results that enhance your skin over time.

At Aisha Khayat Aesthetics, we tailor every treatment to your skin and your goals. Our expert team offers personalised consultations to help you choose the best approach—whether that’s polynucleotides, fillers, or a combination—to achieve your most radiant, confident self.